Azodyl

By Rania Gollakner, BS, DVM, MPH

What is Azodyl®?

Azodyl® is a brand name for a probiotic supplement used to support kidney health in cats and dogs that have kidney disease.

Dietary supplements are substances that can be used to supplement the diet, such as vitamins, minerals, amino acids, herbs, botanicals, enzymes, and probiotics. While many supplements are sold over the counter, they still contain ingredients that have biological effects that should be managed by your veterinarian. Follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label.

There are differences in how countries regulate supplements. In the United States, these substances are not as vigorously regulated by the US Food and Drug Administration (FDA) as other medications, which means they can be sold without the manufacturer proving their effectiveness and safety, and without a guarantee of consistent or accurately reported ingredients. In Canada, products that have been evaluated for quality, safety, and effectiveness by Health Canada and authorized for sale will have a license number on the label.

How does Azodyl® work?

Azodyl® works by adding nitrogen-consuming bacteria to the intestines. These bacteria break down the increased waste products resulting from the kidney’s impaired ability to eliminate them.

How effective is Azodyl®?

Limited studies involving rats, cats, and pigs have found positive results, however other studies have contradicted these results in cats and dogs. Therefore, a treatment trial would be recommended to evaluate effectiveness on a case by case basis.

How is Azodyl® given?

Azodyl® is given by mouth in the form of a capsule. It may be given with or without food. Do not open or crush the capsules; give each capsule whole.

What if I miss giving my pet the supplement?

If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.

Are there any potential side effects or risk factors for this supplement?

Side effects with Azodyl® are rare. Notify your veterinarian if you notice anything unusual while your pet is on this supplement. There are no known risk factors for using Azodyl®.

Are there any drug interactions I should be aware of?

There are no known drug interactions with Azodyl®; however, vitamins, herbal therapies, and supplements have the potential to interact with each other, as well as with prescription and over the counter medications. It is important to tell your veterinarian about any medications (including all vitamins, supplements, or herbal therapies) that your pet is taking.

Is there any monitoring that needs to be done with this supplement?

There is no specific monitoring that needs to be done while your pet is taking this medication. Your veterinarian may monitor your pet to be sure that the medication is working.

How do I store Azodyl®?

Store this supplement in the refrigerator.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.

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