What is deracoxib?
Deracoxib (brand name Deramaxx®) is a non-steroidal anti-inflammatory drug (NSAID) used in dogs to reduce the pain associated with surgery (e.g., orthopedic and dental surgeries) as well as for the treatment of osteoarthritis and other painful conditions or injuries.
How is deracoxib given?
- Give deracoxib by mouth, once daily, as a chewable tablet.
- Give with food to reduce possible gastrointestinal side effects.
- If your pet acts sick or vomits, contact your veterinarian.
This medication takes effect quickly, in about 1 to 2 hours, and your pet’s signs should improve after that.
What if I miss giving my dog the medication?
If you miss a dose, give it when you remember. However, if it is close to time for the next dose, skip the dose you missed, give it at the next scheduled time, and return to the regular dosing schedule. Never give your pet two doses at once or give extra doses.
Are there any potential side effects?
Like other NSAIDs, deracoxib can affect the gastrointestinal tract, with the following side effects:
- diarrhea (most common)
- vomiting
- lack of appetite
- weight loss
Serious adverse reactions associated with this drug may occur without warning and could, in rare cases, lead to death. If any of the following signs develop, stop giving deracoxib and contact your veterinarian immediately:
- decrease in energy level
- incoordination
- aggression
- yellowing of the skin, gums, or white of the eyes
- decrease in appetite
- changes in drinking and urination habits
- changes in skin (scratching, redness, or scabbing)
Never give deracoxib prescribed for one dog in your household to another pet without first consulting your veterinarian. Deracoxib is not approved or recommended for use in cats.
This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease. Most drug-related adverse effects resolve completely when the drug is withdrawn and appropriate veterinary care is initiated.
Are there any risk factors for this medication?
Deracoxib should NOT be used in dogs that:
- have a hypersensitivity to sulfonamides
- are allergic to deracoxib or drugs like it (aspirin, other NSAIDs)
- have bloody stools (black or tarry appearance) or bloody vomit (coffee grounds appearance)
- have a loss of appetite
- have liver or kidney disease
- are dehydrated or are predisposed to dehydration
- are breeding, pregnant, or nursing
- are taking aspirin, other NSAIDs, or corticosteroids
Deracoxib should be used with caution in dogs that:
- have or have had stomach ulcers
- are taking diuretics (e.g., furosemide)
- are old
- have a bleeding disorder
- have heart disease
Are there any drug interactions I should be aware of?
Avoid giving your dog other NSAIDs or corticosteroids while they are taking deracoxib. Certain medications may interact with deracoxib and so it is important to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your dog is taking before starting any new treatment.
Is there any monitoring needed with this medication?
- Your veterinarian should perform baseline bloodwork and urinalysis before your pet starts deracoxib.
- If your dog is taking deracoxib for extended periods (as in the treatment of osteoarthritis), your veterinarian will do periodic blood tests to check liver and kidney function. It is very important to attend these follow-up appointments.
- Your veterinarian may recommend recheck examinations to ensure the medication is working adequately to manage pain.
- At home, monitor for any side effects such as those noted above. If any side effects occur, discontinue the medication and contact your veterinarian.
How do I store deracoxib?
- Ensure deracoxib is stored in a tightly closed container and secured inside a cabinet to prevent accidental ingestion. These chewable tablets can be very tempting to dogs.
- Store in a tightly sealed container at room temperature between 59°F and 86°F (15°C and 30°C).
- Keep the container out of reach of children and pets.
- Store compounded forms of this medication according to the label.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. If your dog receives too much of this medication, it can have serious effects on the gastrointestinal system, liver, or kidneys.
