What is enrofloxacin + silver sulfadiazine otic?
Enrofloxacin + silver sulfadiazine otic (brand name Baytril® Otic) is an antibacterial/antifungal agent used in the treatment of ear infections in dogs and cats. Its use in cats is off-label.
Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada.
In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
How is enrofloxacin + silver sulfadiazine otic given?
- Enrofloxacin + silver sulfadiazine otic comes as a liquid in a bottle with a dropper tip. It is applied topically to the ear canal.
- Shake the medication well before each use.
- You may need assistance when administering ear drops to your pet.
- Tilt your pet’s head so the affected ear faces upwards.
- Use enough drops to ensure that the lesions in the ear and the ear canal are coated. Your veterinarian will recommend the number of drops to be applied.
- Gently massage the ear to ensure that the medication is evenly distributed.
- Avoid handling this product if you are allergic to quinolone compounds.
- Avoid contact with eyes and skin. In case of contact with the skin, wash with soap and water. In case of contact with eyes, flush with water for 15 minutes. Contact your doctor if irritation develops or persists.
This medication will take effect quickly, in about one to two hours, but it may take a few days for effects to be visible.
What if I miss giving my pet the medication?
If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once. It is essential to give the medication for the length of time your veterinarian has recommended, even if your pet appears to feel better.
Are there any potential side effects?
Enrofloxacin + silver sulfadiazine otic may cause the following side effects; if they occur, contact your veterinarian immediately:
- Hearing loss
- Temporary vestibular (balance) disorders (especially in cats)
- Inflamed and red ears (in hypersensitive dogs)
- Swollen joints and lameness (in young animals, especially puppies between 4 and 28 weeks of age)
Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.
Are there any risk factors for this medication?
DO NOT USE enrofloxacin + silver sulfadiazine otic in:
- Dogs with hypersensitivities (allergies) to quinolones or sulfonamides
- Puppies between the ages of 4 weeks and 28 weeks
USE WITH CAUTION in:
- Pets with a history of central nervous system disorders (including seizures)
- Pets with ruptured eardrums
- Pets that are young
- Pets that are pregnant or nursing
Are there any drug interactions I should be aware of?
Certain drugs may interact with enrofloxacin + silver sulfadiazine otic, so be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking.
Is any monitoring needed with this medication?
- Your veterinarian will let you know when and how they want to reassess your pet to ensure the medication is working and not causing side effects.
- At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.
How do I store enrofloxacin/silver sulfadiazine otic?
- Store enrofloxacin + silver sulfadiazine otic in a tightly sealed container, between 40°F and 77°F (4°C and 25°C).
- Protect from direct sunlight.
- Store the bottle in an upright position.
- Keep the container out of reach of children and pets.
What should I do in case of an emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms.
