What is lincomycin?
Lincomycin (brand names: Lincocin®, Lincomix®) is a lincosamide antibiotic used to treat bacterial infections such as skin and bone infections. It is similar to clindamycin, which is used more often than lincomycin.
While its use for certain conditions is FDA-approved for cats and dogs, its use for other conditions and its use in ferrets and birds to treat bacterial infections is off label (extra label). Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.
How is lincomycin given?
- Lincomycin is given by mouth in the form of a tablet, capsule, or liquid solution. It may also be given as an injection in the hospital by a veterinarian.
- Measure liquid forms carefully.
- Give the oral form on an empty stomach, followed by a small amount of water or food to avoid a throat burn from the medication.
- If vomiting occurs when dosed on an empty stomach, give future doses with food.
This medication should take effect within 1 to 2 hours, and while effects may not be visibly obvious, gradual improvements are usually noticeable after a few days.
What if I miss giving my pet the medication?
If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.
Are there any potential side effects?
Lincomycin may cause the following side effects:
- Vomiting
- Diarrhea
- Drooling
Serious adverse reactions may occur. If any of the following signs develop, stop giving lincomycin and contact your veterinarian immediately:
- Continued or severe bloody stools
- Trouble swallowing
- Lack of appetite
- Yellowing of the skin, gums, or eyes
Drug sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.
Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.
Are there any risk factors for this medication?
DO NOT USE lincomycin in:
- Rabbits, hamsters, guinea pigs, or horses
- Pets that are allergic to it or similar drugs
- Pets with a candida fungal infection
- Pets that are very young
USE WITH CAUTION in:
- Pets with liver or kidney disease
- Pets that are pregnant or nursing (although its use is likely safe according to the information available)
Are there any drug interactions I should be aware of?
The following medications should be used with caution when given with lincomycin:
- Cyclosporine
- Erythromycin
Lincomycin may also cause increases in liver values that do not have clinical significance. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.
Is any monitoring needed with this medication?
- Liver and kidney function should be monitored while using this medication.
- Your veterinarian will let you know when and how they want to reassess your pet to ensure the medication is working and not causing side effects.
- At home, monitor for any side effects such as those noted above. If any occur, stop using the medication and contact your veterinarian.
How do I store lincomycin?
- Store this medication at room temperature between 68°F and 77°F (20°C and 25°C) in a tight container.
- Protect from light.
- Keep the container out of reach of children and pets.
What should I do in case of emergency?
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet’s weight and symptoms.
