Aspirin Poisoning in Cats

What is aspirin?

Aspirin (acetylsalicylic acid or ASA) is a common over-the-counter, nonsteroidal anti-inflammatory drug (NSAID) used to treat fever, pain, and inflammation. Aspirin may also be used to prevent the formation of blood clots. It may be the only ingredient in a medication, or it may be part of a combination product containing other medications such as acetaminophen, opioids, antihistamines, decongestants, and caffeine.

Aspirin is one compound in a group of chemicals called salicylates. All salicylates have the potential to cause poisoning. These chemicals may occur in a wide range of products, including pain medications, Pepto-Bismol, wintergreen oil, sunscreen, lip balm, hair and skin care products, toothpaste, wart removers, and pain creams. The risk of poisoning depends on the type of salicylate and the amount to which the pet was exposed.

Aspirin may be used in cats with heart disease to decrease the likelihood of blood clots; however, newer, safer, and more effective anti-platelet drugs are now preferred.

What causes aspirin poisoning?

Aspirin acts by blocking chemical processes that cause inflammation. These processes are also essential for normal gastrointestinal, kidney, and blood clotting functions. When aspirin or salicylates are ingested in excess, the normal chemical processes are disrupted, causing injury to the gastrointestinal tract, kidneys, liver, and clotting mechanisms. Cats are especially sensitive to aspirin and salicylates, so are more vulnerable to poisoning than dogs.

Aspirin and other salicylate-containing products are often found in homes. Poisoning may occur when pets accidentally get into these products and ingest a dose that is too large. In some cases, owners may give aspirin or other salicylates to treat their cat’s pain or gastrointestinal upset before consulting a veterinarian. Aspirin poisoning may occur from a single dose or from repeated dosing. 

Previously existing medical conditions may increase the risk of poisoning (e.g., clotting disorders, kidney disease, or liver disease). Cats already taking steroids or NSAIDs other than aspirin have a higher risk of poisoning.

What are the signs of aspirin poisoning?

Signs of aspirin poisoning vary depending on the dose and product to which the cat was exposed. The most common effects of aspirin or salicylate exposure are vomiting or diarrhea, which may include blood, decreased appetite, and elevated body temperature. Higher doses of aspirin may damage major organs like the liver, kidneys, and central nervous system. Symptoms can start within four to six hours and may last several days.

How is aspirin poisoning treated?

As with all poisoning cases, early intervention is key to successful treatment. Call your veterinarian or Pet Poison Helpline, a 24/7 animal poison center, at 1-800-213-6680, as soon as you realize your pet has consumed aspirin. Your pet’s veterinarian may decontaminate, perform bloodwork, and recommend supportive therapy, which may include hospitalization.

Pet Poison Helpline, an animal poison control center based out of Minneapolis, MN, is available 24/7 for pet owners and veterinary professionals that require assistance treating a potentially poisoned pet. The staff provides treatment advice for poisoning cases of all species, including dogs, cats, birds, small mammals, large animals, and exotic species. As the most cost-effective option for animal poison control care, Pet Poison Helpline’s per-incident fee includes follow-up consultations for the duration of the poison case. Pet Poison Helpline is available in North America by calling 800-213-6680. Additional information can be found online at www.petpoisonhelpline.com